Seahawks Host 49ers in Season Opener at Lumen Field

Lead: The Seattle Seahawks open their 2025 campaign Sunday by welcoming the San Francisco 49ers to Lumen Field at 1:05 p.m. PT, aiming to leverage a revamped offense against a division rival. Nut Graf: After finishing 10-7 yet missing the playoffs last season, Seattle has overhauled its roster-most notably adding QB Sam Darnold and bolstering the defensive front-while San Francisco looks to rebound from a 6-11 finish under Kyle Shanahan by leaning on a healthier Christian McCaffrey and young playmakers.

Kickoff Time and Broadcast

Date & Time: Sunday, September 7 at 1:05 p.m. PT
Venue: Lumen Field, Seattle, Washington
TV: FOX

Key Matchups

Running Game vs. Run Defense: Seattle’s revamped ground attack, boasting Kenneth Walker III and Zach Charbonnet, seeks to exploit a San Francisco front that surrendered 49 rushing touchdowns last year.
Quarterback Duel: New Seahawks signal-caller Sam Darnold aims to start strong against a Niners secondary led by All-Pro safety Talanoa Hufanga.
Edge Rushers: Seattle’s young front, featuring rookie Devon Witherspoon, will battle San Francisco’s revamped offensive line-tested by the return of Trent Williams at tackle.

Injuries and Inactives

Seahawks: Linebacker Uchenna Nwosu and receiver Jake Bobo are inactive, while rookie guard Grey Zabel is available after a strong camp.
49ers: Star receiver Brandon Aiyuk is sidelined for at least six weeks recovering from ACL surgery; Christian McCaffrey, listed as questionable with a calf issue, is expected to play.

How to Watch

Fans can stream the game on the FOX Sports app or tune in via local affiliate channels. Pregame coverage begins at 10:00 a.m. PT, featuring analysis of Seattle’s new-look roster and San Francisco’s bounce-back potential.